Build-a-Cell Workshop #5

August 16 2019, Boston, MA

MIT Building 6, Room 6-120
182 Memorial Drive (Rear)
Cambridge, MA 02139 United States

Thank you all for a great and productive workshop.

Please register by filling this google form.
Please register by July 10 to be included in considerations for travel grant.
If you do not need travel funds, please register by August 12 to be included in our food orders count.

Schedule (draft)
Main proceedings: room 6-120; working groups in main room and in rooms 2-132 and 2-135.
8AM Breakfast, introductions
9AM Framing talks
       9AM George Church
       9.30AM Drew Endy
10AM general discussion, working group introductions
11AM Working groups (all through lunch)
12PM Lunch
3.30PM Working group reports and summaries, plans for the future
5PM End of the meeting

Thursday evening social
Please join us for an informal dinner on Thursday night.
We will meet at 6PM, at the Friendly Toast , located 1 Kendall Square B3101, Camidge, MA 02139.

Friday evening
After the workshop, Friday evening, we are invited to Gingko Bioworks. We will head there after the end of the workshop on campus. If you can, please plan on staying with us. We will talk about the details of the visit and transportation at the workshop.


In addition to the below listed groups, we welcome suggestions for in situ formation of new working groups after the general discussion.

LifeOS group
Building an operating system for life.
google doc link best group

Interlab Group
A list of potential components/subsystems that have already been demonstrated in isolation by differently and could be potentially integrated together in a "synthetic cell” to demonstrate some interesting function. Output is diagram showing the components and some made-up graphs showing what we think we could demonstrate.
google doc link interlab group

PURE that makes PURE/better translation group
Self-replicating translation systems, making and upgrading cell-free protein expression extracts
Expected outcome: white paper review? list of problems that need to be solved to obtain self-replicating PURE
google doc link pure group

In silico cell group
Software for modelling and simulation of synthetic cell metabolism, transport, signaling and circuits
Expected outcome (Aug 2018): list of available codes and protocols, list of needs for inputs and wishes for outputs, start dedicated Git.
Put together a v0.1 simulation of a synthetic cell that has whatever functionality we can muster.
Lead Drew
google doc link in silico group

Questions group
something house science accumulation
google doc link theory group

Tool group
Tools for construction of synthetic cells.
google doc link tool group

Synergy group
This breakout’s discussion was about the need for both top/down and bottom/up processes to understand essential cell functions.
google doc link synergy group

Local info

This part of the MIT campus is accessible by Red line subway, Kendall stop.
There are few hotels walking distance from Building 6, including Le Méridien Boston Cambridge , Residence Inn by Marriott Boston Cambridge , Boston Marriott Cambridge , Royal Sonesta Boston , The Kendall Hotel .
There is also a lot or Airbnb options near Central Square and Kendall Square.
We do not have group rate in any hotel. Depending on interest, we might negotiate group rates for future Workshops.

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